HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylamine → HCID 69506709, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylamine | HCID 7852 | — |
| Reactant | HCID 57447034 | HCID 57447034 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 69506709 | HCID 69506709 | 97.2% |
Reaction Steps
A solution of ethyl 3-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)propanoate (3.45 g, 11.1 mmol), n-propylamine (9.1 mL, 110 mmol), and THF (5 mL) was heated at 80° C. for two days in a high-pressure vessel, allowed to cool to ambient temperature, and concentrated under reduced pressure to provide 3.5 g of 3-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)-N-propylpropanamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08697873B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-aae4eb95a6464f9aad5e002f5cdb416c |
| Source note | uspto-grants-2014_04 |