Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2366628Generated: October 31, 2026

Propylamine → HCID 69506709, compound

https://huagongshe.com/reaction/2366628

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPropylamineHCID 7852—
ReactantHCID 57447034HCID 57447034—
SolventTetrahydrofuranHCID 8028—
ProductHCID 69506709HCID 6950670997.2%

Reaction Steps

A solution of ethyl 3-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)propanoate (3.45 g, 11.1 mmol), n-propylamine (9.1 mL, 110 mmol), and THF (5 mL) was heated at 80° C. for two days in a high-pressure vessel, allowed to cool to ambient temperature, and concentrated under reduced pressure to provide 3.5 g of 3-(2-propyl-1H-imidazo[4,5-c]quinolin-1-yl)-N-propylpropanamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697873B2
Source datasetuspto-grants-2014_04
ORD IDord-aae4eb95a6464f9aad5e002f5cdb416c
Source noteuspto-grants-2014_04