Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | HCID 57447041 | HCID 57447041 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 57447042 | HCID 57447042 | — |
Reaction Steps
A mixture of ethyl 3-(1H-imidazo[4,5-c]quinolin-1-yl)propanoate (4.70 g, 17.5 mmol), THF (5 mL), and methylamine (available as a 40% solution in water, 10 mL) was sealed in a high-pressure vessel, stirred at 100° C. overnight, and concentrated under reduced pressure to provide 4.4 g of 3-(1H-imidazo[4,5-c]quinolin-1-yl)-N-methylpropanamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08697873B2 |
|---|
| Source dataset | uspto-grants-2014_04 |
|---|
| ORD ID | ord-5309d81d2e4348b9af1ffe235a4a8685 |
|---|
| Source note | uspto-grants-2014_04 |
|---|
