Propylamine → HCID 57447043, compound

HRID 2366646Notes

Reaction equation

HRID 2366646 reaction equation
[N:1]1([CH2:14][CH2:15][C:16]([O:18]CC)=O)[C:13]2[C:12]3[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=3[N:6]=[CH:5][C:4]=2[N:3]=[CH:2]1.[CH2:21]([NH2:24])[CH2:22][CH3:23]>>[N:1]1([CH2:14][CH2:15][C:16]([NH:24][CH2:21][CH2:22][CH3:23])=[O:18])[C:13]2[C:12]3[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=3[N:6]=[CH:5][C:4]=2[N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 7852PropylamineHCID 57447041HCID 57447041, compound

Product 1

HCID 57447043HCID 57447043, compound

Procedure

Ethyl 3-(1H-imidazo[4,5-c]quinolin-1-yl)propanoate (3.75 g, 13.9 mmol, prepared as described in Part A of Example 20) was treated with n-propylamine (11.4 mL, 139 mmol) according to the method described in Part B of Example 20 to provide 3.9 g of 3-(1H-imidazo[4,5-c]quinolin-1-yl)-N-propylpropanamide.

Sources & evidence

ORD record
ord-996aa1faa0fe4dc8a0785be71534427d
Source dataset
uspto-grants-2014_04
Patent number
US08697873B2

Reaction notes

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