Diethylamine → N,N-DIETHYL-1-METHYL-PIPERIDINE-4-CARBOXAMIDE

HRID 2366817Notes

Reaction equation

[CH3:1][N:2]1[CH2:7][CH2:6][CH:5]([C:8]([OH:10])=O)[CH2:4][CH2:3]1.S(Cl)(Cl)=O.[CH2:15]([NH:17][CH2:18][CH3:19])[CH3:16]>>[CH2:15]([N:17]([CH2:18][CH3:19])[C:8]([CH:5]1[CH2:4][CH2:3][N:2]([CH3:1])[CH2:7][CH2:6]1)=[O:10])[CH3:16]

Participants

Reactant 3

HCID 8021Diethylamine

HCID 24386Thionyl Chloride

HCID 27369391-Methylpiperidine-4-carboxylic acid

Product 1

HCID 412858N,N-DIETHYL-1-METHYL-PIPERIDINE-4-CARBOXAMIDE

Procedure

reacting 1-methylpiperidine-4-carboxylic acid with thionyl chloride and diethyl amine to yield N,N-diethyl-1-methylpiperidine-4-carboxamide;

Sources & evidence

ORD record: ord-a922d6489af44368990e89cd6114f974
Source dataset: uspto-grants-2014_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08697876B2

Reaction notes

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