HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → (6-Bromopyridin-2-yl)(1-methylpiperidin-4-yl)methanone hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 2,6-Dibromopyridine | HCID 12274 | — |
| Reactant | N,N-DIETHYL-1-METHYL-PIPERIDINE-4-CARBOXAMIDE | HCID 412858 | — |
| Product | (6-Bromopyridin-2-yl)(1-methylpiperidin-4-yl)methanone hydrobromide | HCID 86679073 | — |
Reaction Steps
reacting N,N-diethyl-1-methylpiperidine-4-carboxamide with a solution of 2,6-dibromopyridine and Grignard reagent followed by hydrobromic acid to yield (6-bromopyridin-2-yl)(1-methylpiperidin-4-yl)methanone hydrobromide;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08697876B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-53e29b5148414edc8c5585f4e59b8749 |
| Source note | uspto-grants-2014_04 |