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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2367061Generated: November 1, 2026

Water → HCID 66616023, compound

https://huagongshe.com/reaction/2367061

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantPotassium HydroxideHCID 14797—
ReactantHCID 66616086HCID 66616086—
SolventEthanolHCID 702—
ProductHCID 66616023HCID 66616023—

Reaction Steps

A mixture of methyl 2-(2-bromo-5-fluorophenyl)-2-methylpropanoate (0.529 g, 3.12 mmol, J. Am. Chem. Soc., 2008, 130, 15157-15166), potassium hydroxide (3.2 g, 57 mmol), water (10 mL) and ethanol (30 mL) was refluxed for 20 h.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697877B2
Source datasetuspto-grants-2014_04
ORD IDord-1129d3c7b01547968a2863e9f7d37db0
Source noteuspto-grants-2014_04