Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | HCID 66616016 | HCID 66616016 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66616084 | HCID 66616084 | — |
Reaction Steps
A mixture of 1-(1-benzylpiperidin-4-yl)-5-fluoro-3,3-dimethylindolin-2-one (171 mg, 0.485 mmol, EXAMPLE 44, Step 3), palladium hydroxide (20 wt % on carbon) (85 mg), formic acid (0.372 mL, 9.7 mmol) and ethanol (20 mL) was stirred at 50° C. for 1 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08697877B2 |
|---|
| Source dataset | uspto-grants-2014_04 |
|---|
| ORD ID | ord-0eaf48b0deb048ad955d7f3207d9867d |
|---|
| Source note | uspto-grants-2014_04 |
|---|
