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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2367163Generated: November 3, 2026

Potassium Acetate → 4-Thiazolecarboxylic acid, 2-[(acetyloxy)methyl]-, ethyl ester

https://huagongshe.com/reaction/2367163

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium AcetateHCID 517044—
ReactantEthyl 2-(bromomethyl)-1,3-thiazole-4-carboxylateHCID 11043146—
SolventAcetonitrileHCID 6342—
Product4-Thiazolecarboxylic acid, 2-[(acetyloxy)methyl]-, ethyl esterHCID 67281559—

Reaction Steps

2.7 g (10.80 mmol) of ethyl 2-(bromomethyl)thiazole-4-carboxylate are dissolved in 108 mL of acetonitrile. 2.225 g (22.67 mmol) of potassium acetate are added and the medium is stirred at room temperature for 14 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697883B2
Source datasetuspto-grants-2014_04
ORD IDord-56f3e3f6ea094caaae2b3de53619b5e9
Source noteuspto-grants-2014_04