HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-n4-ethylpyrimidine-2,4-diamine → HCID 58504843, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-n4-ethylpyrimidine-2,4-diamine | HCID 229050 | — |
| Reactant | 3,5-Difluoro-4-formylphenylboronic acid | HCID 16217708 | — |
| Product | HCID 58504843 | HCID 58504843 | 43% |
Reaction Steps
The title compound was prepared following the General Procedure A using: (3,5-difluoro-4-formylphenyl)boronic acid (2.54 g, 13.7 mmol) and 6-chloro-N4-ethyl-2,4-pyrimidinediamine (2.36 g, 13.7 mmol). The solid was triturated with EtOAc and filtered to afford the title compound (1.63 g, 43%) as a yellow solid. LC-MS (ES) m/z=279 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08697685B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-20d4d59012474fadba20e7fae358f2dc |
| Source note | uspto-grants-2014_04 |