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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2367208Generated: November 1, 2026

6-Chloro-n4-ethylpyrimidine-2,4-diamine → HCID 58504843, compound

https://huagongshe.com/reaction/2367208

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-n4-ethylpyrimidine-2,4-diamineHCID 229050—
Reactant3,5-Difluoro-4-formylphenylboronic acidHCID 16217708—
ProductHCID 58504843HCID 5850484343%

Reaction Steps

The title compound was prepared following the General Procedure A using: (3,5-difluoro-4-formylphenyl)boronic acid (2.54 g, 13.7 mmol) and 6-chloro-N4-ethyl-2,4-pyrimidinediamine (2.36 g, 13.7 mmol). The solid was triturated with EtOAc and filtered to afford the title compound (1.63 g, 43%) as a yellow solid. LC-MS (ES) m/z=279 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08697685B2
Source datasetuspto-grants-2014_04
ORD IDord-20d4d59012474fadba20e7fae358f2dc
Source noteuspto-grants-2014_04