Hydrochloric Acid → Hydrochloric Acid

Participants

Reaction Steps

1,1-Dimethylethyl(2S,5R)-5-ethyl-2-{[(phenylmethyl)amino]carbonyl}-4-morpholinecarboxylate (0.551 g, 1.581 mmol) was taken up in HCl in 1,4-dioxane (4 M, 5 mL, 165 mmol) and was stirred at room temperature overnight. The reaction was concentrated to afford a HCl salt of the title compound (0.400 g) as a brown oil. LC-MS (ES) m/z=249 [M+H]+.

Provenance & Evidence