反应详情

67.0 g (0.265 mol) of 3-formamido-2-phenyl-benzo(b)thiophene and 700 milliliters of HCl at 25% are refluxed with stirring for 8 hours. After cooling, it is diluted with water, neutralised by ammonia and the product is dissolved in CH2Cl2. By evaporating the organic phase dried over K2CO3, 58.7 g (98% of theory) of 2-phenyl-3-amino-benzo-(b)thiophene are obtained; yellow plates melting between 110° and 112° C. (cyclohexane).

1. temperatureAfter cooling
2. customBy evaporating the organic phase
3. dry with materialdried over K2CO3, 58.7 g (98% of theory) of 2-phenyl-3-amino-benzo-(b)thiophene
4. customare obtained
5. custommelting between 110° and 112° C.