HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 15700627, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Cyclohexane | HCID 8078 | — |
| Reactant | 3-Formamido-2-phenyl-benzo(b)thiophene | HCID 15700625 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15700627 | HCID 15700627 | — |
Reaction Steps
67.0 g (0.265 mol) of 3-formamido-2-phenyl-benzo(b)thiophene and 700 milliliters of HCl at 25% are refluxed with stirring for 8 hours. After cooling, it is diluted with water, neutralised by ammonia and the product is dissolved in CH2Cl2. By evaporating the organic phase dried over K2CO3, 58.7 g (98% of theory) of 2-phenyl-3-amino-benzo-(b)thiophene are obtained; yellow plates melting between 110° and 112° C. (cyclohexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04157399 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-cfd4f86d07494e81a34f7b9397722571 |
| Source note | uspto-grants-1979_06 |