HCID 67342250, compound → HCID 70655230, compound

Participants

Reaction Conditions

Reaction Steps

To a solution 8-(4-trifluoromethyl-cyclohexenyl)-[1,2,4]triazolo[1,5-a]pyridine-2-ylamine (CAS 1329673-42-8, US 20110201605) (30 mg, 0.106 mmol) in methanol (5 mL) was added 10% Pd/C (30 mg), and the reaction mixture was allowed to stir at 25° C. for 2 hours under hydrogen balloon atmosphere. The reaction mixture was filtered through a bed of celite and the filtrate was evaporated off in vacuo yield the title compound as a white solid (30 mg, 99%) which was used in the next step without further purification. MS ISP (m/e): 285.2 (100) [(M+H)+].

Provenance & Evidence