Hydrochloric Acid → 2-Aminobenzene-1,4-diol hydrochloride

HRID 2368067Notes

Reaction equation

HRID 2368067 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11])([O-])=O.[ClH:12]>[C].[Pd]>[ClH:12].[NH2:1][C:4]1[CH:9]=[C:8]([OH:10])[CH:7]=[CH:6][C:5]=1[OH:11]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 43139181,4-Benzenediol, 2-nitro-

Product 1

HCID 136850472-Aminobenzene-1,4-diol hydrochloride

Reagents, catalysts & solvents 1

HCID 178418390HCID 178418390, compoundCatalyst

Procedure

A suspension of 2-nitrobenzene-1,4-diol (1.00 g) and 10% palladium carbon (containing water (50%), 1.00 g) in 1 M hydrochloric acid (13 mL) was stirred at room temperature for 5 hr under a hydrogen atmosphere. The reaction mixture was filtered, the filtrate was concentrated under reduced pressure, and the obtained solid was washed with ethyl acetate to give the title compound (949 mg).

Workup

  1. filtrationThe reaction mixture was filtered
  2. concentrationthe filtrate was concentrated under reduced pressure
  3. washthe obtained solid was washed with ethyl acetate

Sources & evidence

ORD record
ord-6fca3bfb201147458a9d136b374616c1
Source dataset
uspto-grants-2014_04
Patent number
US08703758B2

Reaction notes

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