HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Hydroxyethyl)piperazine → HCID 12703405, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Hydroxyethyl)piperazine | HCID 7677 | — |
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | HCID 21315986 | HCID 21315986 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 12703405 | HCID 12703405 | — |
Reaction Steps
7-Methyl-10-chloro-thieno[3,4-b][1,5]benzoxazepine (Example 7) is reacted with 20 ml. of N-(2-hydroxyethyl)-piperazine in 20 ml. of dry toluene as described in Example 1, giving the base compound which is further reacted with fumaric acid, giving the desired product as the fumarate salt, m.p. 178°-180° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04157444 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-1c48e5666c8942a78df5a72803bc85e1 |
| Source note | uspto-grants-1979_06 |