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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2368123Generated: November 3, 2026

HCID 57517503, compound → 4-(Cyclopropylmethoxy)-3-fluorobenzenamine

https://huagongshe.com/reaction/2368123

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57517503HCID 57517503—
CatalystHCID 178418390HCID 178418390—
SolventMethanolHCID 887—
Product4-(Cyclopropylmethoxy)-3-fluorobenzenamineHCID 1962724496.8%

Reaction Steps

A suspension of 1-(cyclopropylmethoxy)-2-fluoro-4-nitrobenzene (18.3 g) and 5% palladium carbon (containing water (50%), 1.84 g) in methanol (289 mL) was stirred for 3 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (15.2 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08703758B2
Source datasetuspto-grants-2014_04
ORD IDord-2bc80886d5f54fa9af817617c089e82f
Source noteuspto-grants-2014_04