HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57517503, compound → 4-(Cyclopropylmethoxy)-3-fluorobenzenamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57517503 | HCID 57517503 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-(Cyclopropylmethoxy)-3-fluorobenzenamine | HCID 19627244 | 96.8% |
Reaction Steps
A suspension of 1-(cyclopropylmethoxy)-2-fluoro-4-nitrobenzene (18.3 g) and 5% palladium carbon (containing water (50%), 1.84 g) in methanol (289 mL) was stirred for 3 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to give the title compound (15.2 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703758B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-2bc80886d5f54fa9af817617c089e82f |
| Source note | uspto-grants-2014_04 |