Phosphorus pentachloride → HCID 21315985, compound

HRID 236816Notes

Reaction equation

HRID 236816 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:11][C:10]3=[CH:12][S:13][CH:14]=[C:9]3[C:8](=O)[NH:7][C:6]=2[CH:16]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:18]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:11][C:10]3=[CH:12][S:13][CH:14]=[C:9]3[C:8]([Cl:18])=[N:7][C:6]=2[CH:16]=1

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 12703384HCID 12703384, compound

Product 1

HCID 21315985HCID 21315985, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A 4.0 g. portion of 7-chloro-thieno[3,4-b][1,5]benzoxazepin-10(9H)-one (Example 4) and 4.0 g. of phosphorus pentachloride in 100 ml. of dry toluene are refluxed for 41/2 hours concentrated and triturated with toluene, giving 7,10-dichlorothieno[3,4-b][1,5]benzoxazepine.

Workup

  1. concentrationconcentrated
  2. customtriturated with toluene

Sources & evidence

ORD record
ord-4ee08cdfdf7a4a91afac86b13b1c24d1
Source dataset
uspto-grants-1979_06
Patent number
US04157444

Reaction notes

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