Sulfuryl chloride → HCID 12581869, compound

HRID 236818Notes

Reaction equation

HRID 236818 reaction equation
[CH:1]1[S:2][CH:3]=[C:4]2[C:10]=1[C:9](=[O:11])[NH:8][C:7]1[CH:12]=[CH:13][CH:14]=[CH:15][C:6]=1[S:5]2.S(Cl)([Cl:19])(=O)=O>C(Cl)Cl>[Cl:19][C:3]1[S:2][CH:1]=[C:10]2[C:9](=[O:11])[NH:8][C:7]3[CH:12]=[CH:13][CH:14]=[CH:15][C:6]=3[S:5][C:4]=12

Participants

4

Reactant 2

HCID 24648Sulfuryl chlorideHCID 12581867HCID 12581867, compound

Product 1

HCID 12581869HCID 12581869, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A suspension of 1.16 g. of thieno[3,4-b][1,5]-benzothiazepin-10(9H)-one in 20 ml. of methylene chloride was treated with 0.81 g of sulfuryl chloride as in Example 12 to give 3-chlorothieno[3,4-b][1,5]benzothiazepin-10(9H)-one as a white crystal, m.p. 287°-288° C.

Workup

  1. additionA suspension of 1.16 g

Sources & evidence

ORD record
ord-69d7eb3b457e456184bd55ec9f0e45f3
Source dataset
uspto-grants-1979_06
Patent number
US04157444

Reaction notes

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