Trifluoroacetic acid → HCID 87288485, compound

Participants

Reaction Steps

The compound from step 1 (12.9 g) is solubilised in 25 ml of CH2Cl2 and 25 ml of trifluoroacetic acid is added at 0° C. The mixture is stirred at ambient temperature for 3 hours. When the reaction is complete, the reaction mixture is evaporated to dryness. The residue is taken up 3 times with cyclohexane and the mixture is re-evaporated to remove the excess TFA. Slightly brown oil, 13.4 g (99%).

Provenance & Evidence