HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Difluoroazetidine → HCID 70116466, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Difluoroazetidine | HCID 2758248 | — |
| Reactant | 3-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acid | HCID 70098054 | — |
| Product | HCID 70116466 | HCID 70116466 | 26% |
Reaction Steps
According to the general method described in step 3 of example 53, reaction of 3,3-difluoroazetidine with 3-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acid provided the title compound as yellow powder (26%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703768B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-bb4b314740fe4dd6a768814d812f5e77 |
| Source note | uspto-grants-2014_04 |