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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2368309Generated: November 1, 2026

3-Hydroxyazetidine → HCID 58548390, compound

https://huagongshe.com/reaction/2368309

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-HydroxyazetidineHCID 1514290—
Reactant3-{[6-Cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acidHCID 70098054—
ProductHCID 58548390HCID 585483908%

Reaction Steps

According to the general method described in step 3 of example 53, reaction of 3-hydroxy-azetidine with 3-{[6-cyclopropyl-3-(pyrimidin-5-ylamino)-pyridine-2-carbonyl]-amino}-isonicotinic acid provided the title compound (8%) as light yellow powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08703768B2
Source datasetuspto-grants-2014_04
ORD IDord-1a4f107c685f444fb5095b6079fe0820
Source noteuspto-grants-2014_04