反应详情

To a solution of azetidin-1-yl-(2-methyl-4-nitro-2H-pyrazol-3-yl)methanone (268 mg, 1.28 mmol) in ethanol (4.5 ml) was added Pd/C 10% (72 mg, 67.7 μmol) and the reaction mixture was stirred at r.t. under a hydrogen atmosphere for 6 h. The reaction mixture was filtered and concentrated in vacuo and the off-white solid was used without further purification in the next step.

1. filtrationThe reaction mixture was filtered
2. concentrationconcentrated in vacuo
3. customthe off-white solid was used without further purification in the next step