Hydrochloric Acid → HCID 57513606, compound

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Reaction Steps

[1-(5-Benzyl-4-phenyl-thiazol-2-ylcarbamoyl)-1-methyl-ethyl]-carbamic acid tert-butyl ester (6.4 g) was stirred overnight in freshly prepared HCl (g)/EtOAc solution (150 mL). Evaporation of the solvent gave the title compound as the hydrochloride salt. 1H NMR (400 MHz, DMSO-D6) δ 1.62 (s, 6H) 4.24 (s, 2H) 7.16-7.25 (m, 3H) 7.30 (d, J=7.58 Hz, 2H) 7.37 (s, 1H) 7.41-7.47 (m, 2H) 7.58-7.63 (m, 2H) 8.64 (s, 3H). m/z 352.1 (MH+).

Provenance & Evidence