Hydrazine → HCID 43564610, 화합물

HRID 2368530노트

반응식

HRID 2368530 반응식
[CH3:1][N:2]([CH2:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)[C:3](=[O:7])[C:4]([O-])=[O:5].[NH2:15][NH2:16]>CCO>[NH:15]([C:4](=[O:5])[C:3]([N:2]([CH3:1])[CH2:8][C:9]1[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=1)=[O:7])[NH2:16]

참가 물질

4

반응물 2

HCID 9321HydrazineHCID 86677559HCID 86677559, 화합물

생성물 1

HCID 43564610HCID 43564610, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

반응 조건

온도
80 °C

실험 절차

A mixture of 2-(methyl(pyridin-4-ylmethyl)amino)-2-oxoacetate (77) (0.96 g, 4.61 mmol) and hydrazine (0.21 mL, 5.82 mmol) in EtOH (15 mL) was stirred at 80° C. for 18 h. The solvent was removed in vacuo to provide 2-hydrazinyl-N-methyl-2-oxo-N-(pyridin-4-ylmethyl)acetamide (78) as a pale yellow solid. This product was directly used in the next step reaction without further purification.

후처리

  1. customThe solvent was removed in vacuo

출처 및 근거

ORD 기록
ord-9635a43748174e5398c03d007afdcbf0
출처 데이터셋
uspto-grants-2014_04
특허 번호
US08703776B2

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