Hydrazine → HCID 43564610, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-(methyl(pyridin-4-ylmethyl)amino)-2-oxoacetate (77) (0.96 g, 4.61 mmol) and hydrazine (0.21 mL, 5.82 mmol) in EtOH (15 mL) was stirred at 80° C. for 18 h. The solvent was removed in vacuo to provide 2-hydrazinyl-N-methyl-2-oxo-N-(pyridin-4-ylmethyl)acetamide (78) as a pale yellow solid. This product was directly used in the next step reaction without further purification.

Provenance & Evidence