HCID 86664895, compound → HCID 86664894, compound

HRID 2368666Notes

Reaction equation

HRID 2368666 reaction equation
[NH2:1][C:2]1[C:11]([N+:12]([O-])=O)=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[C:4]([O:15][CH2:16][CH:17]([F:19])[F:18])[N:3]=1>[Ni].C1COCC1.CO>[NH2:12][C:11]1[C:2]([NH2:1])=[N:3][C:4]([O:15][CH2:16][CH:17]([F:19])[F:18])=[C:5]([CH:10]=1)[C:6]([O:8][CH3:9])=[O:7]

Participants

5

Reactant 1

HCID 86664895HCID 86664895, compound

Product 1

HCID 86664894HCID 86664894, compound

Reagents, catalysts & solvents 3

HCID 935NickelCatalystHCID 887MethanolSolventHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 154d by hydrogenation of the product obtained in (803a) using Raney nickel in THF and methanol.

Workup

  1. customPrepared analogously to example 154d by hydrogenation of the product

Sources & evidence

ORD record
ord-76c832c10d45413d85790f1a60ca1110
Source dataset
uspto-grants-2014_04
Patent number
US08703796B2

Reaction notes

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