5-Bromo-6-ethoxy-3-nitropyridin-2-amine → HCID 67355989, compound

HRID 2368668Notes

Reaction equation

HRID 2368668 reaction equation
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([Br:11])=[C:4]([O:12][CH2:13][CH3:14])[N:3]=1>[Ni].C1COCC1>[Br:11][C:5]1[CH:6]=[C:7]([NH2:8])[C:2]([NH2:1])=[N:3][C:4]=1[O:12][CH2:13][CH3:14]

Participants

4

Reactant 1

HCID 185105005-Bromo-6-ethoxy-3-nitropyridin-2-amine

Product 1

HCID 67355989HCID 67355989, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 154d by hydrogenation of the product obtained in (842a) using Raney nickel in THF.

Workup

  1. customPrepared analogously to example 154d by hydrogenation of the product

Sources & evidence

ORD record
ord-79c984d2861f4cafa9bcaadebeb45563
Source dataset
uspto-grants-2014_04
Patent number
US08703796B2

Reaction notes

Loading…