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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2368782Generated: November 2, 2026

HCID 23154377, compound → HCID 46831580, compound

https://huagongshe.com/reaction/2368782

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23154377HCID 23154377—
ReactantHCID 67455735HCID 67455735—
ProductHCID 46831580HCID 46831580—

Reaction Steps

The title compound was prepared by condensation reaction between ethyl (1S)-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-indene-5-carboxylate and 4-methyl-N(3)-(4-pyridin-4-ylpyrimidin-2-yl)benzene-1,3-diamine, according to the procedure described in Step C of EXAMPLE 11. MS (M+1)=520.27. 1HNMR (DMSO-d6, ppm): δ 10.14 (s, 1H); 9.04 (s, 1H); 8.07 (d, J=4.4 Hz, 2H); 8.55 (d, J=4.8 Hz, 1H); 8.06 (s, 1H); 8.04 (d, J=4.4 Hz, 2H); 7.78 (s, 1H); 7.75 (d, J=8.8 Hz, 1H); 7.45 (d, J=7.6 Hz, 1H); 7.44 (d, J=4.8 Hz, 1H); 7.35 (d, J=7.6 Hz, 1H); 7.18 (d, J=8.8 Hz, 1H); 4.31 (t, J=7.2 Hz, 1H); 2.0-3.0 (m, 10H); 2.19 (s, 3H); 2.12 (s, 3H); 2.04 (m, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08703771B2
Source datasetuspto-grants-2014_04
ORD IDord-f422d302cc3c44ecb41761b308fa6977
Source noteuspto-grants-2014_04