HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23154377, compound → HCID 46831580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23154377 | HCID 23154377 | — |
| Reactant | HCID 67455735 | HCID 67455735 | — |
| Product | HCID 46831580 | HCID 46831580 | — |
Reaction Steps
The title compound was prepared by condensation reaction between ethyl (1S)-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-indene-5-carboxylate and 4-methyl-N(3)-(4-pyridin-4-ylpyrimidin-2-yl)benzene-1,3-diamine, according to the procedure described in Step C of EXAMPLE 11. MS (M+1)=520.27. 1HNMR (DMSO-d6, ppm): δ 10.14 (s, 1H); 9.04 (s, 1H); 8.07 (d, J=4.4 Hz, 2H); 8.55 (d, J=4.8 Hz, 1H); 8.06 (s, 1H); 8.04 (d, J=4.4 Hz, 2H); 7.78 (s, 1H); 7.75 (d, J=8.8 Hz, 1H); 7.45 (d, J=7.6 Hz, 1H); 7.44 (d, J=4.8 Hz, 1H); 7.35 (d, J=7.6 Hz, 1H); 7.18 (d, J=8.8 Hz, 1H); 4.31 (t, J=7.2 Hz, 1H); 2.0-3.0 (m, 10H); 2.19 (s, 3H); 2.12 (s, 3H); 2.04 (m, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703771B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-f422d302cc3c44ecb41761b308fa6977 |
| Source note | uspto-grants-2014_04 |