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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2368808Generated: November 1, 2026

Hydrochloric Acid → HCID 68227296, compound

https://huagongshe.com/reaction/2368808

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 68227587HCID 68227587—
SolventTetrahydrofuranHCID 8028—
ProductHCID 68227296HCID 68227296—

Reaction Steps

The title compound was prepared in analogy to example 1, step 5 from 10-{4-[(R)-2,2,2-trifluoro-1-(4-methoxy-benzyloxy)-ethyl]-phenyl}-1,4-dioxa-10-aza-dispiro[4.2.4.2]tetradecan-9-one (4.91 g) by treatment with 2 M HCl (58.3 ml) in THF (68.2 ml) as a white solid. (3.5 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08703807B2
Source datasetuspto-grants-2014_04
ORD IDord-b74cc24a2c14424bb5732972b261db97
Source noteuspto-grants-2014_04