Hydrochloric Acid → HCID 21315543, compound

Participants

Reaction Conditions

Reaction Steps

To 70 parts of 4-picoline, also called 4-methylpyridine, was added 270 parts of a 21.5% solution of hydrogen choride in isopropanol, then 118 parts 4-vinylpyridine was added and the resulting solution heated to 60° C. for 10 hours. The mixture was cooled to 30° C. and filtered to give 148 parts 1-[2-(4-pyridyl)ethyl]-4-picolinium chloride hydrochloride. The 1-[2-(4-pyridyl)ethyl]-4-picolinium chloride hydrochloride was then reacted with acrylontrile as in Example 13 to give 4-[tris(2-carboxyethyl)methyl]pyridine.

Provenance & Evidence