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HRID2369262

反应详情

EQUATION

反应方程式

HRID 2369262 的结构方程式

REACTANTS

反应物

2
结构：CN1CCC(=O)CC1
HCID74049

1-Methyl-4-piperidone

C6H11NO

结构：Cc1ccc(N(N)CCc2ccc(C)nc2)cc1
HCID2827520

1-(4-methylphenyl)-1-[2-(6-methylpyridin-3-yl)ethyl]hydrazine

C15H19N3

PRODUCTS

生成物

1
结构：Cc1ccc(N(CCc2ccc(C)nc2)N=C2CCN(C)CC2)cc1
HCID49765790

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccccc1
溶剂HCID241

Benzene

C6H6

PROCEDURE

实验过程

The crude N-[2-(6-methyl-pyridin-3-yl)-ethyl]-N-p-tolyl-hydrazine was dissolved in benzene (20 cm3) and 4 Å molecular sieves added (˜5 g), followed by 1-methylpiperidin-4-one (346 μL, 3.0 mmol). The reaction was heated to reflux for 2 hours, cooled, and filtered. Solvent was removed in vacuo to yield a crude orange oil.

WORKUP

后处理

  1. addition4 Å molecular sieves added (˜5 g)
  2. temperatureThe reaction was heated
  3. temperatureto reflux for 2 hours
  4. temperaturecooled
  5. filtrationfiltered
  6. customSolvent was removed in vacuo
  7. customto yield a crude orange oil