HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-piperidone → N'-(1-Methyl-piperidin-4-ylidene)-N-[2-(6-methyl-pyridin-3-yl)-ethyl]-N-p-tolyl-hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | 1-(4-Methylphenyl)-1-[2-(6-methylpyridin-3-yl)ethyl]hydrazine | HCID 2827520 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | N'-(1-Methyl-piperidin-4-ylidene)-N-[2-(6-methyl-pyridin-3-yl)-ethyl]-N-p-tolyl-hydrazine | HCID 49765790 | — |
Reaction Steps
The crude N-[2-(6-methyl-pyridin-3-yl)-ethyl]-N-p-tolyl-hydrazine was dissolved in benzene (20 cm3) and 4 Å molecular sieves added (˜5 g), followed by 1-methylpiperidin-4-one (346 μL, 3.0 mmol). The reaction was heated to reflux for 2 hours, cooled, and filtered. Solvent was removed in vacuo to yield a crude orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08703952B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-112ea48064524b4e8fcdf1b792b423ab |
| Source note | uspto-grants-2014_04 |