HRID236983

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID807

Iodine

$结构：C=C1CC[C@H](O)C/C1=C/C=C1\CCC[C@]2(C)[C@@H]([C@H](C)CCCC(C)C)CC[C@@H]12$

HCID5280795

Vitamin D3

C27H44O

PRODUCTS

生成物

$结构：C=C1CC[C@H](O)C/C1=C\C=C1/CCC[C@@]2(C)C1CC[C@@H]2[C@H](C)CCCC(C)C$

HCID12303099

未命名化合物

收率 61.3%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID8058

n-Hexane

C6H14

PROCEDURE

实验过程

To a solution of Vitamin D3 (750 mgs) in hexane (20 ml) was added iodine (2 mgs). After stirring for 1 hr. at 20° the solution was washed with aqueous sodium thiosulphate, water and dried over sodium sulphate. After removal of the solvent, chromatography afforded trans-vitamin D3 (460mgs).

WORKUP

后处理

washat 20° the solution was washed with aqueous sodium thiosulphate, water
dry with materialdried over sodium sulphate
customAfter removal of the solvent, chromatography