HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxypiperidine → 1-(4-(Oxazol-2-yl)phenyl)piperidin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxypiperidine | HCID 23293 | — |
| Reactant | 2-(4-Bromophenyl)oxazole | HCID 11075032 | — |
| Product | 1-(4-(Oxazol-2-yl)phenyl)piperidin-3-ol | HCID 71226940 | 45% |
Reaction Steps
1-(4-(Oxazol-2-yl)phenyl)piperidin-3-ol (245 mg, 1.00 mmol) was synthesized, in 45% yield, as described in General Procedure B using 2-(4-bromophenyl)oxazole (500 mg, 2.232 mmol) and piperidin-3-ol (451 mg, 4.46 mmol). Anal. Calcd. for C14H16N2O2 m/z 244.2, found: 245.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710049B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-603344b271854a86aa52ff01deb160ff |
| Source note | uspto-grants-2014_04 |