Hydrochloric Acid → HCID 67450266, compound

Participants

Reaction Steps

Suspend 8-(2-chlorophenyl)-2-methyl-6-(4-methylpiperazin-1-yl)-9-(2-methylsulfonylethyl)purine (11.3 g, 25.2 mmol) in ethanol (150 mL) and add 1 N aqueous hydrogen chloride solution (6.29 mL, 25.2 mmol, 1 eq). Allow the mixture to stir overnight and concentrate under reduced pressure. Collect the precipitated solids by filtration, wash with acetone, and dry under vacuum to afford the title compound (10.6 g). ES/MS m/z 449 (M+1).

Provenance & Evidence