HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium thiocyanate → HCID 178527827, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium thiocyanate | HCID 15666 | — |
| Reactant | Ethanone, 2-hydroxy-2-phenyl-1-(3-pyridinyl)- | HCID 20460416 | — |
| Solvent | 1-Propanol | HCID 1031 | — |
| Product | HCID 178527827 | HCID 178527827 | 44.3% |
Reaction Steps
3-Pyridyl α-hydroxybenzyl ketone (8.15 g; 38.3 mmoles) was reacted with 7.5 g (0.1 mole) of ammonium thiocyanate in 1-propanol heated at reflux to give 4.3 g of 4-phenyl-5-(3-pyridyl)-1H-2-imidazolethiol, m.p. 317°-323° recrystallized from DMF:H2O (2:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04159338 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-df3f4f4c76a4471aa88dca99b5379b2a |
| Source note | uspto-grants-1979_06 |