HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → Morphine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 64-31-3 | HCID 5464280 | — |
| Solvent | Water | HCID 962 | — |
| Product | Morphine | HCID 5288826 | 81% |
Reaction Steps
1 g (2.64 mmol) of morphine sulfate was dissolved in 100 mL of distilled water and then NaHCO3 (3.79 g, 45 mmol) was added. Morphine free base precipitated out. Precipitated morphine free base was then filtered and left to dry overnight in a dessicator under partial vacuum. 0.613 g (81% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710069B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-59fbb916bc7f41908e35fcb808c2a17e |
| Source note | uspto-grants-2014_04 |