反应详情

4-Phenyl-5-(3-pyridyl)-1H-2-imidazolethiol (2.0 g; 7.9 mmoles) was reacted with 5.0 g (50 mmoles) of tetrafluoroethylene and the crude product purified by chromatography on Silicar CCNo. 7 with chloroform to afford 800 mg of 4-phenyl 5-(3-pyridyl)-2-(1,1,2,2-tetrafluoroethylthio)-1H-imidazole, m.p. 153°-154° (recrystallized from toluene).

1. customthe crude product purified by chromatography on Silicar CCNo
2. custom7 with chloroform to afford
3. custom800 mg of 4-phenyl 5-(3-pyridyl)-2-(1,1,2,2-tetrafluoroethylthio)-1H-imidazole, m.p. 153°-154° (recrystallized from toluene)