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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2370195Generated: October 30, 2026

4-(Trifluoromethyl)phenylboronic acid → 3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyran-4(3H)-one

https://huagongshe.com/reaction/2370195

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)phenylboronic acidHCID 2734389—
Reactant3-iodo-4,4-dimethoxytetrahydro-2H-pyranHCID 58075384—
Product3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyran-4(3H)-oneHCID 58075307—

Reaction Steps

4-(trifluoromethyl)phenylboronic acid was reacted as described in Intermediate X(2) with 3-iodo-4,4-dimethoxytetrahydro-2H-pyran (Intermediate X(1)) to give 3-(4-(trifluoromethyl)phenyl)dihydro-2H-pyran-4(3H)-one (Intermediate Z(2)).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08710061B2
Source datasetuspto-grants-2014_04
ORD IDord-33b6c727fdd94443a44f8f339ef5cd45
Source noteuspto-grants-2014_04