Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237024Generated: October 25, 2026

1-(3-Chlorophenyl)piperazine → 1-(3-Chlorophenyl)-4-(4-nitrophenyl)sulfonylpiperazine

https://huagongshe.com/reaction/237024

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Chlorophenyl)piperazineHCID 1355—
Reactant4-Nitrobenzenesulfonyl chlorideHCID 7404—
SolventTriethylamineHCID 8471—
Product1-(3-Chlorophenyl)-4-(4-nitrophenyl)sulfonylpiperazineHCID 1019725—

Reaction Steps

In the manner given in Example 1A, p-nitrobenzenesulfonyl chloride, 1-(m-chlorophenyl)piperazine, and triethylamine are stirred at reflux to give 1-[(p-nitrophenyl)sulfonyl]-4-(m-chlorophenyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04159331
Source datasetuspto-grants-1979_06
ORD IDord-dd6266a2b2ba43b992466510e0d45622
Source noteuspto-grants-1979_06