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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237028Generated: October 30, 2026

1-[(p-Nitrophenyl)sulfonyl]-4-(o-bromophenyl)piperazine → 1-[(p-Aminophenyl)sulfonyl]-4-(o-bromophenyl)piperazine

https://huagongshe.com/reaction/237028

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(p-Nitrophenyl)sulfonyl]-4-(o-bromophenyl)piperazineHCID 21314828—
Catalysttitanium(III) trichlorideHCID 10313229—
Product1-[(p-Aminophenyl)sulfonyl]-4-(o-bromophenyl)piperazineHCID 21314832—

Reaction Steps

In the manner given in Example 5B, 1-[(p-nitrophenyl)sulfonyl]-4-(o-bromophenyl)piperazine is reduced with titanium chloride (TiCl3) to give 1-[(p-aminophenyl)sulfonyl]-4-(o-bromophenyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04159331
Source datasetuspto-grants-1979_06
ORD IDord-c734c2eef8e64071ab1762709b9102f7
Source noteuspto-grants-1979_06