Thionyl Chloride → HCID 86668135, compound

Participants

Reaction Conditions

Reaction Steps

The title compound was prepared according to General Method 10. 4-[3-(3-Fluoro-4-hydroxymethyl-phenyl)-4,4-dimethyl-5-oxo-2-thioxo-imidazolidin-1-yl]-2-trifluoromethyl-benzonitrile (0.5 g, 1.14 mmol) was dissolved in thionyl chloride (5 mL) and the solution was stirred at 100° C. for 12 h. The reaction mixture was concentrated under reduced pressure to obtain 300 mg of product.

Provenance & Evidence