HCID 21314869, compound → HCID 21314935, compound

HRID 237044Notes

Reaction equation

HRID 237044 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:13]2[CH2:18][CH2:17][N:16]([C:19]3[CH:24]=[C:23]([C:25]([F:28])([F:27])[F:26])[CH:22]=[C:21]([C:29]([F:32])([F:31])[F:30])[CH:20]=3)[CH2:15][CH2:14]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-])=O.[H][H]>O=[Pt]=O>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:13]2[CH2:14][CH2:15][N:16]([C:19]3[CH:20]=[C:21]([C:29]([F:30])([F:31])[F:32])[CH:22]=[C:23]([C:25]([F:28])([F:27])[F:26])[CH:24]=3)[CH2:17][CH2:18]2)(=[O:11])=[O:12])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 21314869HCID 21314869, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21314935HCID 21314935, compound

Reagents, catalysts & solvents 1

HCID 345198Adams' catalystCatalyst

Procedure

In the manner given in Example 5B, 1-[(p-nitrophenyl)sulfonyl]-4-[3,5-di(trifluoromethyl)-phenyl]piperazine is reduced with hydrogen over PtO2 to give 1-[(p-aminophenyl)sulfonyl]-4-[3,5-di(trifluoromethyl)phenyl]piperazine.

Sources & evidence

ORD record
ord-349cdc457cb54559a7411f57013492bb
Source dataset
uspto-grants-1979_06
Patent number
US04159331

Reaction notes

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