2,6-Dimethoxy-4-aminopyrimidine → HCID 72226655, compound

HRID 2370455Notes

Reaction equation

HRID 2370455 reaction equation
[CH3:1][NH:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[OH:12])[C:6](O)=[O:7].COC1N=C(N)C=C(OC)[N:16]=1>>[CH3:1][NH:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][C:11]=1[OH:12])[C:6]([NH2:16])=[O:7]

Participants

3

Reactant 2

HCID 767892,6-Dimethoxy-4-aminopyrimidineHCID 51063613HCID 51063613, compound

Product 1

HCID 72226655HCID 72226655, compoundYield 67%

Procedure

Using 3-methylamino-4-hydroxylbenzoic acid and 2,6-dimethoxy-4-aminopyrimidine as materials, compound 3 is synthesized following a similar method as in Example 28. Yield: 67%.

Sources & evidence

ORD record
ord-0b67e14b01124da5a1948876dee3c038
Source dataset
uspto-grants-2014_04
Patent number
US08710098B2

Reaction notes

Loading…