4-Nitrobenzenesulfonyl chloride → HCID 19684907, compound

HRID 237047Notes

Reaction equation

HRID 237047 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10](Cl)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:14][O:15][C:16]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][C:17]=1[S:24]([N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1)(=[O:26])=[O:25]>C(N(CC)CC)C>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:30]2[CH2:31][CH2:32][N:27]([S:24]([C:17]3[CH:18]=[CH:19][C:20]([O:22][CH3:23])=[CH:21][C:16]=3[O:15][CH3:14])(=[O:26])=[O:25])[CH2:28][CH2:29]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 74044-Nitrobenzenesulfonyl chlorideHCID 2758388HCID 2758388, compound

Product 1

HCID 19684907HCID 19684907, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In the manner given in Example 1A, p-nitrobenzenesulfonyl chloride, 1-[(2,4-dimethoxyphenyl)-sulfonyl]piperazine and triethylamine are stirred at reflux to give 1-[(p-nitrophenyl)sulfonyl]-4-[(2,4-dimethoxyphenyl)sulfonyl]piperazine.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-2fcf4846baf04bbcab062b6b0aa4c2d3
Source dataset
uspto-grants-1979_06
Patent number
US04159331

Reaction notes

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