4-Nitrobenzenesulfonyl chloride → HCID 21314875, compound

HRID 237049Notes

Reaction equation

HRID 237049 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10](Cl)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].[F:14][C:15]1[CH:16]=[C:17]([S:24]([N:27]2[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]2)(=[O:26])=[O:25])[CH:18]=[CH:19][C:20]=1[CH2:21][CH2:22][CH3:23]>C(N(CC)CC)C>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:30]2[CH2:29][CH2:28][N:27]([S:24]([C:17]3[CH:18]=[CH:19][C:20]([CH2:21][CH2:22][CH3:23])=[C:15]([F:14])[CH:16]=3)(=[O:25])=[O:26])[CH2:32][CH2:31]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 74044-Nitrobenzenesulfonyl chlorideHCID 21314830HCID 21314830, compound

Product 1

HCID 21314875HCID 21314875, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In the manner given in Example 1A, p-nitrobenzenesulfonyl chloride, 1-[(3-fluoro-4-propylphenyl)sulfonyl]piperazine and triethylamine are stirred at reflux to give 1-[(p-nitrophenyl)sulfonyl]-4-[(3-fluoro-4-propylphenyl)sulfonyl]piperazine.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-c04e1af0437a42a5b828084fe52377a8
Source dataset
uspto-grants-1979_06
Patent number
US04159331

Reaction notes

Loading…