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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 237058Generated: October 26, 2026

5-(3-Methylbenzyl)-2-thiouracil → 2-[2-(5-Methyl-4-imidazolylmethylthio)ethylamino]-5-(4-methylbenzyl)-4-pyrimidone dihydrochloride

https://huagongshe.com/reaction/237058

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3-Methylbenzyl)-2-thiouracilHCID 10082671—
Reactant2-[2-(5-Methyl-4-imidazolylmethylthio)ethylamino]-5-(3-methylbenzyl)-4-pyrimidone dihydrochlorideHCID 23346180—
Product2-[2-(5-Methyl-4-imidazolylmethylthio)ethylamino]-5-(4-methylbenzyl)-4-pyrimidone dihydrochlorideHCID 23346197—

Reaction Steps

In a similar manner 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(3-methylbenzyl)-4-pyrimidone dihydrochloride m.p. 203.5°-205° (ex ethanol) may be prepared from 5-(3-methylbenzyl)-2-thiouracil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04159329
Source datasetuspto-grants-1979_06
ORD IDord-2d33e5c7285146a1a0b63e61f080f043
Source noteuspto-grants-1979_06