HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 23346179, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 5-(4-Chlorobenzyl)-2-methylthiopyrimid-4-one | HCID 12945980 | — |
| Reactant | 2-{[(3-Bromopyridin-2-yl)methyl]sulfanyl}ethan-1-amine | HCID 12951527 | — |
| Product | HCID 23346179 | HCID 23346179 | — |
Reaction Steps
5-(4-Chlorobenzyl)-2-methylthio-4-pyrimidone (1.2 g) was reacted with 2-(3-bromo-2-pyridylmethylthio)ethylamine (1.1 g) according to the procedure of Example 2. The reaction mixture was acidified with dilute ethanolic hydrogen chloride, evaporated to dryness and the residue recrystallised from ethanol/water to give 2-[2-(3-bromo-2-pyridylmethylthio)ethylamino]-5-(4-chlorobenzyl)-4-pyrimidone monohydrochloride, m.p. 215°-218° (decomposes).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04159329 |
| Source dataset | uspto-grants-1979_06 |
| ORD ID | ord-74eef8316ff341e6b7fcb4a7c482fbdc |
| Source note | uspto-grants-1979_06 |