HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Trifluoroacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68195399 | HCID 68195399 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 68194822 | HCID 68194822 | — |
Reaction Steps
To a solution of tert-butyl 7′-amino-1′H-spiro[cyclopropane-1,4′-isoquinoline]-2′(3′H)-carboxylate (0.350 g, 1.276 mmol) in CH2Cl2 (8 ml) was added trifluoroacetic acid (0.983 ml, 12.76 mmol). The reaction was stirred overnight and concentrated to provide the title compound as a trifluoroacetic acid salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08710065B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-9f3373c186c84dd6bc2e4f8fe75777d3 |
| Source note | uspto-grants-2014_04 |