huagongshe.com
HRID2370728

反应详情

EQUATION

反应方程式

HRID 2370728 的结构方程式

REACTANTS

反应物

1
结构：CC(C)(C)OC(=O)N[C@H]1CC[C@@H](Oc2ccc3cnccc3c2Cl)CC1
HCID178454059

未命名化合物

PRODUCTS

生成物

1
结构：N[C@H]1CC[C@@H](Oc2ccc3cnccc3c2Cl)CC1
HCID178511693

未命名化合物

收率 100.1%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

50 mg (0.13 mmol) cis-[4-(5-Chloro-isoquinolin-6-yloxy)-cyclohexyl]carbamic acid tert-butyl ester (12) were dissolved in ethanol/2N HCl (1:1) and stirred at room temperature until complete conversion could be detected (LCMS). Evaporation of the solvent furnished 36 mg of the title compound as hydrochloride. Rt=0.71 min (Method #1). Detected mass: 277.2/279.2 (M+H+).

WORKUP

后处理

  1. customEvaporation of the solvent